THE NOVEL POSITIVE ALLOSTERIC MODULATOR OF THE GABAB RECEPTOR, KK-92A, SUPPRESSES ALCOHOL SELF-ADMINISTRATION AND CUE-INDUCED REINSTATEMENT OF ALCOHOL SEEKING IN RATS

Positive allosteric modulators (PAMs) of the GABAB receptor (GABAB PAMs) are of interest in the addiction field due to their ability to suppress several behaviors motivated by drugs of abuse.KK-92A is a novel GABAB PAM found to attenuate intravenous self-administration of nicotine and reinstatement of nicotine seeking in rats.This present study was

The worldwide population rise corroborated with the raise of the health-care standards have generated an escalation of the antibiotic production and uncontrolled usage.The subsequent Cargo effects of this escalation have led to an increase of the antibiotic resistance rates, Romania is in the top of the EU countries regarding the antibiotic resista

Additive manufacturing (AM) has gained prominence over the last 15 years and become a viable manufacturing option.Since there is great industrial interest to implement serial production of products using AM, the education of engineers in design for additive manufacturing (DfAM) is important today.DfAM extends on design for manufacturing to provide

In recent years, a large and growing body of literature has addressed the energy-efficient resource management problem in data centers.Due to the fact that cooling costs Ski de fond - Enfant - Bottes still remain the major portion of the total data center energy cost, thermal-aware resource management techniques have been employed to make additiona

Abstract Simultaneous tracking of multiple persons in real-world environments is an active research field and several approaches have been proposed, based on a variety of features and algorithms.Recently, there has been a growing interest in organizing systematic evaluations Primer to compare the various techniques.Unfortunately, the lack of common